來看看 Foobar2000 官方 FAQ

http://www.foobar2000.org/FAQ

Does foobar2000 sound better than other players?

No. Most of 「sound quality differences」 people 「hear」 are placebo effect (at least with real music), as actual differences in produced sound data are below their noise floor (1 or 2 last bits in 16bit samples). foobar2000 has sound processing features such as software resampling or 24bit output on new high-end soundcards, but most of the other mainstream players are capable of doing the same by now.

除非你覺得比作者更了解 Foobar2000。